SPICE is a lab-created drug that can cause severe hallucinations and make users pass out.
Before the ban on psychoactive substances in 2016, it was being sold either over the counter or online under a variety of brand names such as Annihilation and GoCaine.
Users can suffer vomiting, seizures, terrifying hallucinations and severe psychotic episodes after consuming the drug.
It is highly addictive with withdrawal symptoms said to be worse than coming off crack or heroin.
Spice appears particularly rife in Birmingham and Manchester, where a number of users have been hospitalised after taking the drug.
It has been dubbed the "zombie drug" because of the effect it can have on users, who are often seen staggering around.
An ex-spice addict described being on the drug as feeling "brain dead".
"They say people look like zombies, and that’s how it feels."
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